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From medical images to multiple‐biomarker microarrays
Author(s) -
Wagner Robert F.
Publication year - 2007
Publication title -
medical physics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.473
H-Index - 180
eISSN - 2473-4209
pISSN - 0094-2405
DOI - 10.1118/1.2805252
Subject(s) - medical imaging , biomarker , dna microarray , computational biology , medical physics , computer science , medicine , artificial intelligence , biology , genetics , gene expression , gene
A favorite cliché, often attributed to Yogi Berra, is “Prediction is difficult, especially about the future!” In this brief review, we shall recall some historical difficulties in predicting the future of diagnostic medical imaging—in particular, the modern technologies of CT and MRI—and examine the analogous situation in the emerging technology of diagnostic microarrays for the multiple‐biomarker problem. All of these technologies began their lives as ill‐conditioned problems, i.e., there was insufficient data to solve the central problem at hand.