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Reconstruction of dynamic gated cardiac SPECT
Author(s) -
Jin Mingwu,
Yang Yongyi,
King Michael A.
Publication year - 2006
Publication title -
medical physics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.473
H-Index - 180
eISSN - 2473-4209
pISSN - 0094-2405
DOI - 10.1118/1.2358201
Subject(s) - gated spect , single photon emission computed tomography , iterative reconstruction , imaging phantom , spect imaging , computer science , dynamic imaging , image resolution , myocardial perfusion imaging , artificial intelligence , smoothness , computer vision , nuclear medicine , perfusion , mathematics , image processing , image (mathematics) , medicine , radiology , digital image processing , heart failure , mathematical analysis , ejection fraction
In this paper we propose an image reconstruction procedure which aims to unify gated single photon emission computed tomography (SPECT) and dynamic SPECT into a single method. We divide the cardiac cycle into a number of gate intervals as in gated SPECT, but treat the tracer distribution for each gate as a time‐varying signal. By using both dynamic and motion‐compensated temporal regularization, our reconstruction procedure will produce an image sequence that shows both cardiac motion and time‐varying tracer distribution simultaneously. To demonstrate the proposed reconstruction method, we simulated gated cardiac perfusion imaging using the gated mathematical cardiac‐torso (gMCAT) phantom with Tc99m‐Teboroxime as the imaging agent. Our results show that the proposed method can produce more accurate reconstruction of gated dynamic images than independent reconstruction of individual gate frames with spatial smoothness alone. In particular, our results show that the former could improve the contrast to noise ratio of a simulated perfusion defect by as much as 100% when compared to the latter.