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Po‐Thur Eve General‐16: Development and Application of a Visualization and Navigation System for Stereotactic Deep‐Brain Neurosurgeries
Author(s) -
Guo T,
Finnis K,
Parrent A,
Peters T
Publication year - 2006
Publication title -
medical physics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.473
H-Index - 180
eISSN - 2473-4209
pISSN - 0094-2405
DOI - 10.1118/1.2244643
Subject(s) - deep brain stimulation , pallidotomy , stereotactic surgery , thalamotomy , medicine , subthalamic nucleus , surgical planning , brain atlas , visualization , neurosurgery , medical physics , computer science , parkinson's disease , radiology , artificial intelligence , disease , pathology
This work presents the development and application of a neurosurgical visualization and navigation system. Integrated with a digitized and segmented brain atlas, an electrophysiological database, and collections of final surgical targets of previous patients, this system provides valuable assistance in pre‐operative planning and intra‐operative guidance of stereotactic deep‐brain neurosurgical procedures for the treatment of Parkinson's disease, chronic pain, and essential tremor. The fusion of standardized functional and anatomical information, once registered to individual patient images, facilitates the delineation of surgical targets, surrounding structures, as well as functional borders. Three retrospective studies and one prospective study were conducted to assess the surgical target localization efficiency of this system, which is capable of non‐rigid registration, interactive manipulation and processing of clinical image data. The surgical target locations identified by an experienced stereotactic neurosurgeon using multiple electrophysiological exploratory trajectories were compared with those located by a non‐expert using this system on 36 thalamotomy, pallidotomy, thalamic deep brain stimulation (DBS), and subthalamic nucleus (STN) DBS procedures. The average displacement between the surgical target locations in both groups was 1.85±0.96mm, 1.87±0.82mm, 1.84±0.85mm, and 1.65±0.71mm for each category of surgeries respectively, indicating promising utilization of our system in stereotactic deep‐brain neurosurgical procedures, and demonstrating its capability of accurate surgical target initiation.