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Estimation of radiation dose at various depths for commonly used radionuclides in radiosynoviorthesis in a tissue equivalent material
Author(s) -
Tandon Pankaj,
Malpani B. L.,
Venkatesh Meera,
Bhatt B. C.
Publication year - 2006
Publication title -
medical physics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.473
H-Index - 180
eISSN - 2473-4209
pISSN - 0094-2405
DOI - 10.1118/1.2219089
Subject(s) - radionuclide , nuclear medicine , imaging phantom , dosimetry , thermoluminescence , materials science , equivalent dose , absorbed dose , thermoluminescent dosimeter , calibration , cumulative dose , synovial joint , radiochemistry , irradiation , medicine , chemistry , physics , nuclear physics , dosimeter , articular cartilage , alternative medicine , pathology , quantum mechanics , osteoarthritis
The purpose of the paper is to report on the dose estimation studies at various depths for the commonly used beta‐emitting Y90 , Ho166 , Sm153 , P32 , and Lu177 radionuclides in a phantom fabricated using the poly methyl methacrylate tissue equivalent material having a density of 1.19 gm ∕ cc , by using thermoluminescent dosemeters. GAFChromic MD‐55 films were used to calculate the calibration factor for the thermoluminescent micro‐rods used in our study. It is observed that Y90 delivers the highest dose at 1 mm amongst the radionuclides tested followed by P32 , Ho166 , Sm153 , and Lu177 , whereas the cumulative dose received by the joint was found to be more for P32 followed by Y90 , Ho166 , Sm153 , and Lu177 . The highest therapeutic range obtained is 3.1 mm for Sm153 amongst the tested radionuclides. The dose values obtained for all the above‐mentioned radionuclides can serve as reference material for those researchers and clinicians who are interested in selection of the radionuclide for the type of joint treated and the amount of dose necessary to be delivered to the synovial membrane.