Premium
CCPM Symposium I ‐ 02: Diffuse optical imaging of the neuro‐metabolic‐vascular relationship during brain activation
Author(s) -
Boas D
Publication year - 2005
Publication title -
medical physics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.473
H-Index - 180
eISSN - 2473-4209
pISSN - 0094-2405
DOI - 10.1118/1.2030968
Subject(s) - positron emission tomography , neuroimaging , functional magnetic resonance imaging , neuroscience , magnetic resonance imaging , functional imaging , brain activity and meditation , diffuse optical imaging , metabolic activity , optical imaging , human brain , premovement neuronal activity , medicine , psychology , radiology , tomography , electroencephalography , physiology , physics , optics
The ability and interest in functional imaging of the human brain has grown with the advent of positron emission tomography (PET) and functional magnetic resonance tomography (fMRI). These imaging techniques are leading to a better understanding of the healthy, diseased, and injured functioning brain. Diffuse optical imaging is a non‐invasive, portable, and relatively inexpensive method that complements PET and fMRI with the ability to continuously monitor the hemodynamic, metabolic, and possibly neuronal activity state of the brain, and to measure populations of subjects and paradigms not amendable to PET or fMRI. All of these methods are predominantly sensitive to the hemodynamic parameters of the brain which arise from the neuronal and metabolic activity. During this talk, I will discuss the contributions of optical imaging to understanding the relationship between neuronal, metabolic, and vascular activity within the brain. Better knowledge of this relationship will guide the development of better treatments and improve the utility of diagnostic imaging methods.