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Are dose calculations during dose optimization in brachytherapy necessary?
Author(s) -
Lahanas M.,
Baltas D.
Publication year - 2003
Publication title -
medical physics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.473
H-Index - 180
eISSN - 2473-4209
pISSN - 0094-2405
DOI - 10.1118/1.1580483
Subject(s) - brachytherapy , dosimetry , computation , sampling (signal processing) , mathematical optimization , computer science , mathematics , algorithm , nuclear medicine , medical physics , physics , radiation therapy , medicine , radiology , filter (signal processing) , computer vision
We consider the problem of anatomy based dose optimization in brachytherapy. A calculation method for some objective functions and their derivatives is proposed which significantly reduces the number of required operations. The optimization in some cases, ignoring a preprocessing step, is independent of the number of sampling points. The idea is that some of the objectives and their derivatives used for dose optimization do not require the explicit calculation of dose values. Dose optimization with the new modified computation method for the objectives and derivatives is, depending on the number of sampling points, up to 100 times faster than the conventional method with dose calculation.