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Thresholds for detecting and characterizing focal lesions using steady‐state MR elastography
Author(s) -
Doyley Marvin M.,
Weaver John B.,
Van Houten Elijah E. W.,
Kennedy Francis E.,
Paulsen Keith D.
Publication year - 2003
Publication title -
medical physics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.473
H-Index - 180
eISSN - 2473-4209
pISSN - 0094-2405
DOI - 10.1118/1.1556607
Subject(s) - elastography , shear modulus , contrast (vision) , modulus , materials science , magnetic resonance imaging , elastic modulus , ultrasound , optics , nuclear magnetic resonance , biomedical engineering , radiology , medicine , physics , composite material
An objective contrast‐detail analysis was performed in this study to assess the low contrast detectability of a clinical prototype harmonic magnetic resonance elastographic imaging system. Elastographic imaging was performed on gelatin phantoms containing spherical inclusions of varying size and modulus contrast. The results demonstrate that lesions as small as 5 mm can be detected with a minimum modulus contrast of 14 dB. However, the shear modulus of such small lesions was not accurately recovered. In general, the shear modulus of larger focal lesions was accurately (i.e., within 25% of the true value) recovered. The minimum modulus contrast needed to detect focal lesions was observed to decrease with increasing lesion size.