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Pulsed‐microwave‐induced thermoacoustic tomography: Filtered backprojection in a circular measurement configuration
Author(s) -
Xu Minghua,
Wang Lihong V.
Publication year - 2002
Publication title -
medical physics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.473
H-Index - 180
eISSN - 2473-4209
pISSN - 0094-2405
DOI - 10.1118/1.1493778
Subject(s) - imaging phantom , thermoacoustics , optics , microwave , iterative reconstruction , tomography , image resolution , point spread function , physics , microwave imaging , resolution (logic) , medical imaging , full width at half maximum , acoustics , computer science , computer vision , artificial intelligence , quantum mechanics
Our study on pulsed‐microwave‐induced thermoacoustic tomography in biological tissues is presented. A filtered backprojection algorithm based on rigorous theory is used to reconstruct the cross‐sectional image from a thermoacoustic measurement in a circular configuration that encloses the sample under study. Specific details describing the measurement of thermoacoustic waves and the implementation of the reconstruction algorithm are discussed. A two‐dimensional (2D) phantom sample with 2 mm features can be imaged faithfully. Through numerical simulation, the full width half‐maximum (FWHM) of the point‐spread function (PSF) is calculated to estimate the spatial resolution. The results demonstrate that the circular measurement configuration combined with the filtered backprojection method is a promising technique for detecting small tumors buried in biological tissues by utilizing microwave absorption contrast and ultrasound spatial resolution (∼mm).