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Monte Carlo‐aided dosimetry of the Theragenics TheraSeed ® Model 200 103 Pd interstitial brachytherapy seed
Author(s) -
Monroe James I.,
Williamson Jeffrey F.
Publication year - 2002
Publication title -
medical physics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.473
H-Index - 180
eISSN - 2473-4209
pISSN - 0094-2405
DOI - 10.1118/1.1460876
Subject(s) - dosimetry , brachytherapy , kerma , monte carlo method , nuclear medicine , anisotropy , ionization chamber , materials science , physics , optics , medicine , mathematics , radiation therapy , ionization , ion , statistics , quantum mechanics
A dosimetric study of a103 Pd seed for permanent interstitial brachytherapy, the Theragenics Corporation Model 200 (TheraSeed ® ), has been undertaken utilizing Monte Carlo photon‐transport (MCPT) simulations. All dosimetric quantities recommended by the American Association of Physicists in Medicine (AAPM) Task Group 43 (TG‐43) [Med. Phys. 22 , 209–234 (1995)] report have been calculated. This source contains graphite pellets coated with palladium metal, within which the radioactive103 Pd is distributed. Due to the significant influence of this metal coating thickness on the dose distribution, two coating thicknesses, 2.2 μm (light seed, representing currently available seeds) and 10.5 μm (heavy seed, representing reactor‐produced seeds available before 1994), were analyzed. Quantities determined are the following: dose rate constant, radial dose function, anisotropy function, anisotropy factor, anisotropy constant, and “along and away” dose tables. The National Institute of Standards and Technology (NIST) Wide Angle Free Air Chamber (WAFAC) standard for air‐kerma strength( S K , N 99 ) was simulated, allowing a comparison to measured dosimetry data normalized to S K , N 99 . The calculated dose‐rate constants are 0.691 (light seed) and 0.694 cGy h −1 U −1 (heavy seed), where 1 U = 1 μ Gy ⋅ m 2 ⋅ h − 1, in contrast to the recommended TG‐43 value of 0.74 cGy h −1 U −1 and the value, 0.665 cGy h −1 U −1 , recommended by AAPM report 69 [Med. Phys. 27 , 634–642 (2000)]. Anisotropy constants( 1 / r 2weighted average, r ⩾ 1 cm ) are 0.862 and 0.884 for the light seed and heavy seed, respectively. A generalization of the AAPM formalism [Med. Phys. 27 , 634–642] for evaluating the time‐dependent ratio of an administered‐to‐prescribed dose is presented. The findings of this study, in combination with 5% corrections applied to WAFAC measurements performed in 1999, imply that changes in the AAPM's recommended ratios as large as 6%, are indicated.