Open AccessProspective prediction and control of image properties in model-based material decomposition for spectral CT
Author(s) -
Wenying Wang,
Matthew Tivnan,
Grace J. Gang,
J. Webster Stayman
Publication year - 2020
Publication title -
medical imaging 2020: physics of medical imaging
Language(s) - English
Resource type - Conference proceedings
SCImago Journal Rank - 0.192
H-Index - 176
pISSN - 0277-786X
DOI - 10.1117/12.2549777
Subject(s) - regularization (linguistics) , computer science , image resolution , noise reduction , iterative reconstruction , noise (video) , spectral imaging , algorithm , artificial intelligence , pattern recognition (psychology) , image (mathematics) , optics , physics
Model-based material decomposition (MBMD) directly estimates the material densities from the spectral CT data and has found opportunities for dose reduction via physical and statistical modeling and advanced regularization. However, image properties such as spatial resolution, noise, and cross-basis response in the context of material decomposition are dependent on regularization, and high-dimensional exhaustive sweeping of regularization parameters is suboptimal. In this work, we proposed a set of prediction tools for generalized local impulse response (LIR) that characterizes both in-basis spatial resolution and cross-basis response, and noise correlation prospectively. The accuracy of noise predictor was validated in a simulation study, comparing predicted and measured in- and cross-basis noise correlations. Employing these predictors, we composed a specialized regularization for cross-talk reduction and showed that such prediction tools are promising for task-based optimization in spectral CT applications.