Open AccessRole of ultrasound in the diagnosis of very early-onset inflammatory bowel disease in children: a report of three cases
Author(s) -
Takahiro Hosokawa,
Yutaka Tanami,
Yumiko Sato,
Ryusuke Nambu,
Itaru Iwama,
Eiji Oguma
Publication year - 2022
Publication title -
medical ultrasonography
Language(s) - English
Resource type - Journals
eISSN - 2066-8643
pISSN - 1844-4172
DOI - 10.11152/mu-3273
Subject(s) - medicine , inflammatory bowel disease , gastroenterology , inflammation , ultrasound , disease , mesentery , short bowel syndrome , pathology , parenteral nutrition , radiology
Very early-onset inflammatory bowel disease (VEO-IBD) is defined as IBD onset before 6 years of age and some cases are caused by unique monogenic disorders that require specific treatments such as stem cell transplantation. We identified three children with VEO-IBD of whom two had monogenic disorders. In cases 1 and 2, ultrasound revealed isolated colonic distribution and the loss of wall stratification. In case 3, mesentery inflammation was evident. Bowel ultrasound showed variable findings due to differences in the inflammation distribution within the bowel. In order to diagnose VEO-IBD, sonographersshould carefully evaluate the intestinal wall thickness and stratification and the distribution of inflammation in the intestine and mesentery. These findings may aid the diagnosis of VEO-IBD.