Modeling Transport and Deposition Efficiency of Oblate and Prolate Nano- and Micro-particles in a Virtual Model of the Human Airway | Zendy

Elise Holmstedt | Zendy; Hans O. Åkerstedt | Zendy; T. Staffan Lundström | Zendy; Sofie Högberg | Zendy

Open Access

Modeling Transport and Deposition Efficiency of Oblate and Prolate Nano- and Micro-particles in a Virtual Model of the Human Airway

Author(s) -

Elise Holmstedt,

Hans O. Åkerstedt,

T. Staffan Lundström,

Sofie Högberg

Publication year - 2016

Publication title -

journal of fluids engineering

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.529

H-Index - 103

eISSN - 1528-901X

pISSN - 0098-2202

DOI - 10.1115/1.4032934

Subject(s) - oblate spheroid , aspect ratio (aeronautics) , prolate spheroid , brownian motion , microscale chemistry , deposition (geology) , particle (ecology) , physics , reynolds number , particle size , mechanics , materials science , molecular physics , classical mechanics , chemistry , turbulence , optoelectronics , geology , mathematics , paleontology , mathematics education , sediment , oceanography , quantum mechanics

A model for the motion and deposition of oblate and prolate spheroids in the nano- and microscale was developed. The aim was to mimic the environment of the human lung, but the model is general and can be applied for different flows and geometries for small nonspherical particle Stokes and Reynolds numbers. A study of the motion and orientation of a single oblate and prolate particle has been done yielding that Brownian motion disturbs the Jeffery orbits for small particles. Prolate microparticles still display distinguishable orbits while oblate particles of the same size do not. A statistical study was done comparing the deposition efficiencies of oblate and prolate spheroids of different size and aspect ratio observing that smaller particles have higher deposition rate for lower aspect ratio while larger particles have higher deposition rates for large aspect ratio.

Validerad; 2016; Nivå 2; 20160816 (andbra)

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