Open AccessPeriodontal disease in Paget�s disease of bone
Author(s) -
Niccolò Nuti,
Marco Ferrari
Publication year - 2015
Publication title -
clinical cases in mineral and bone metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.314
H-Index - 32
eISSN - 1971-3266
pISSN - 1724-8914
DOI - 10.11138/ccmbm/2015.12.2.195
Subject(s) - medicine , bisphosphonate , paget's disease of bone , disease , periodontal disease , bone remodeling , osteonecrosis of the jaw , dentistry , bone disease , anticipation (artificial intelligence) , paget disease , osteoporosis , artificial intelligence , computer science
A 59-year-old man suffering from Paget's disease of bone and periodontal disease was examined in anticipation of bisphosphonate treatment. The previous therapy with clodronate resulted ineffective and markers of bone turnover were markedly elevated. Periodontal disease was correctly approached and treated with an excellent outcome. 5 mg zoledronate iv infusion induced a remarkable reduction of bone markers which persisted on time within the normal range. After zoledronate treatment no signs of osteonecrosis of the jaw (ONJ) were observed. A correct management of periodontal disease is mandatory in pagetic patients on bisphosphonate treatment.