Open AccessEvaluation Of The Mutagenic Potential Of The Polyphenol Extract From Blueberries In The Ames Test
Author(s) -
Zarina Shulgau,
Shynggys Sergazy,
A.M. Zhulikeeva,
A.Y. Dautov,
A. E. Gulyaev,
Л. В. Коваленко,
L.D. Belotserkovtseva,
N.S. Kavushevskaya,
A.V. Logutenko
Publication year - 2021
Publication title -
eurasian journal of applied biotechnology
Language(s) - English
Resource type - Journals
eISSN - 2617-1147
pISSN - 2617-1139
DOI - 10.11134/btp.1.2021.3
Subject(s) - salmonella , ames test , polyphenol , food science , chemistry , microbiology and biotechnology , mutation , biology , gene , genetics , bacteria , biochemistry , antioxidant
In this research, mutagenic properties of blueberry polyphenol extract were studied in gene mutation induction test (Ames test) on four strains of Salmonella typhimurium TA98, TA100, TA1535, TA1537. None of the strains of Salmonella typhimurium showed statistically reliable dose-dependent increase in number of revertant colonies in the presence of investigated drug in the studied dose range from 4,0 to 40,0 mg/ml relative to baseline of spontaneous mutations. The blueberry extract does not have any mutagenic activity in the researched dose range in relation to TA98, TA100, TA1535, TA1537 strains of Salmonella typhimurium.