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Improvements in skeletal muscle strength and cardiac function induced by resveratrol during exercise training contribute to enhanced exercise performance in rats
Author(s) -
Dolinsky Ver W.,
Jones Kelvin E.,
Sidhu Robinder S.,
Haykowsky Mark,
Czubryt Michael P.,
Gordon Tessa,
Dyck Jason R. B.
Publication year - 2012
Publication title -
the journal of physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.802
H-Index - 240
eISSN - 1469-7793
pISSN - 0022-3751
DOI - 10.1113/jphysiol.2012.230490
Subject(s) - resveratrol , isometric exercise , skeletal muscle , medicine , endocrinology , cardiac function curve , vastus lateralis muscle , endurance training , treadmill , cardiac muscle , chemistry , heart failure , pharmacology
Key points• Resveratrol, an antioxidant found in red wine, has beneficial effects on cardiac and skeletal muscle function, similar to the effects of endurance exercise training. • Combining resveratrol supplementation with exercise training augments the beneficial effects of exercise alone. • We show that endurance capacity is enhanced in rats whose diet includes resveratrol during a 12 week endurance‐training programme. • Increased endurance was associated with increases in skeletal muscle force, cardiac function, and oxidative metabolism. • Our results establish that resveratrol is an effective ergogenic aid that enhances exercise performance over exercise alone.