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Carotid chemoreceptor modulation of blood flow during exercise in healthy humans
Author(s) -
Stickland Michael K.,
Fuhr Desi P.,
Haykowsky Mark J.,
Jones Kelvin E.,
Paterson D. Ian,
Ezekowitz Justin A.,
McMurtry M. Sean
Publication year - 2011
Publication title -
the journal of physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.802
H-Index - 240
eISSN - 1469-7793
pISSN - 0022-3751
DOI - 10.1113/jphysiol.2011.218099
Subject(s) - chemoreceptor , carotid body , blood flow , blood pressure , medicine , sympathetic activity , endocrinology , receptor , cardiology , carotid arteries , anesthesia , heart rate
Non‐technical summary Exercise causes an increase in sympathetic activity which helps to redistribute blood flow while maintaining blood pressure. The exact mechanisms that regulate sympathetic activity and blood flow during exercise are not completely understood. By modulating the activity of a specific chemical receptor (the carotid chemoreceptor), we showed that this receptor contributes to the regulation of blood flow during exercise in healthy subjects. These findings demonstrate the importance of the carotid chemoreceptor in the regulation of blood flow during exercise in health.