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The influence of carbohydrate–protein co‐ingestion following endurance exercise on myofibrillar and mitochondrial protein synthesis
Author(s) -
Breen Leigh,
Philp Andrew,
Witard Oliver C.,
Jackman Sarah R.,
Selby Anna,
Smith Ken,
Baar Keith,
Tipton Kevin D.
Publication year - 2011
Publication title -
the journal of physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.802
H-Index - 240
eISSN - 1469-7793
pISSN - 0022-3751
DOI - 10.1113/jphysiol.2011.211888
Subject(s) - myofibril , carbohydrate , medicine , chemistry , endocrinology , ingestion , phosphorylation , biochemistry
Non‐technical summary A single bout of exercise stimulates the production of new muscle proteins. Furthermore, ingesting protein in close proximity to exercise enhances the metabolic response. Long‐term exercise training promotes muscle adaptation, and the mode of exercise performed determines the type of proteins that are made. To date, the types of proteins that are made when protein is ingested after endurance exercise are not known. We report that when well‐trained male cyclists ingest protein with a carbohydrate drink after a high‐intensity ride, production of proteins responsible for muscle contraction is increased. Proteins responsible for aerobic energy production are not responsive to protein feeding. Furthermore, specific signals within the muscle that control protein synthesis are responsive to protein ingestion, providing a potential mechanism to underpin our primary findings. These results suggest that protein feeding after intense endurance exercise may be important in maintaining the structural quality and power generating capacity of the muscle.