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An expanding view of dynamic electrical coupling in the mammalian retina
Author(s) -
Cafaro Jon,
Schwartz Gregory W.,
Grimes William N.
Publication year - 2011
Publication title -
the journal of physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.802
H-Index - 240
eISSN - 1469-7793
pISSN - 0022-3751
DOI - 10.1113/jphysiol.2011.205740
Subject(s) - retina , coupling (piping) , neuroscience , physics , computer science , biology , materials science , metallurgy
Gap junctions are a ubiquitous feature of the mammalian brain, and while researchers have been gaining an appreciation for their physiological complexity over the last several decades, many of their functional roles within identified neural circuits remain elusive. All five primary neuronal cell types in the retina (photoreceptors, horizontal, bipolar, amacrine and ganglion cells) make gap junction-mediated synaptic connections, providing an approachable model system for exploring the roles that gap junctions play in neural signal processing.