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Microarrays and the microscope: balancing throughput with resolution
Author(s) -
Coppola Giovanni,
Geschwind Daniel H.
Publication year - 2006
Publication title -
the journal of physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.802
H-Index - 240
eISSN - 1469-7793
pISSN - 0022-3751
DOI - 10.1113/jphysiol.2006.112623
Subject(s) - throughput , microarray , computer science , dna microarray , resolution (logic) , computational biology , biology , artificial intelligence , gene expression , gene , genetics , telecommunications , wireless
The cellular complexity of the brain is a major issue in the planning, execution and interpretation of microarray studies. Recent technical advances allow for high‐throughput study of specific cell populations and circuits. Here we review representative examples of currently available methods that allow high resolution and specificity in brain microarray studies, while maintaining the goal of comprehensive, high‐throughput analysis.