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EEG oscillations at 600 Hz are macroscopic markers for cortical spike bursts
Author(s) -
Baker Stuart N.,
Gabriel Curio,
Lemon Roger N.
Publication year - 2003
Publication title -
the journal of physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.802
H-Index - 240
eISSN - 1469-7793
pISSN - 0022-3751
DOI - 10.1113/jphysiol.2003.045674
Subject(s) - neuroscience , electroencephalography , excitatory postsynaptic potential , somatosensory system , spike (software development) , postsynaptic potential , somatosensory evoked potential , population , physics , spike and wave , electrophysiology , psychology , biology , inhibitory postsynaptic potential , medicine , computer science , biochemistry , receptor , software engineering , environmental health
The human electroencephalogram (EEG) is generated predominantly by synchronised cortical excitatory postsynaptic potentials oscillating at frequencies <100 Hz. Unusually, EEG responses to electrical nerve stimulation contain brief bursts of high‐frequency (600 Hz) wavelets. Here we show, in awake monkeys, that a subset of primary somatosensory cortex single units consistently fires both bursts and single spikes phase‐locked to EEG wavelets. Spike bursts were also evoked by tactile stimuli, proving that this is a natural response mode. EEG wavelets at 600 Hz may therefore permit non‐invasive assessment of population spike timing in human cortex.