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Axon conduction failure under in vivo conditions in crayfish.
Author(s) -
Smith D O
Publication year - 1983
Publication title -
the journal of physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.802
H-Index - 240
eISSN - 1469-7793
pISSN - 0022-3751
DOI - 10.1113/jphysiol.1983.sp014942
Subject(s) - axon , crayfish , in vivo , thermal conduction , block (permutation group theory) , biophysics , electrophysiology , stimulation , neuroscience , nerve conduction velocity , nerve conduction , chemistry , biology , anatomy , materials science , medicine , microbiology and biotechnology , mathematics , fishery , composite material , geometry
Action potential discharge in an identified axon was recorded in ‘intact’ crayfish, and conduction block occurred during prolonged high‐frequency activity. These in vivo recordings were also used to trigger stimulation of the same axon in vitro; conduction block occurred during high‐frequency bursts in small terminal branches. Quantal release was distributed in a bimodal fashion, with numerous failures, due to these occurrences of conduction block. These results indicate that conduction block may occur in intact animals and that it may also cause selective recruitment of specific nerve terminals during normal behaviour.