Plasma vasopressin concentration in the anaesthetized dog before, during and after atrial distension. | Zendy

Ledsome J R | Zendy; Ngsee J | Zendy; Wilson N | Zendy

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Plasma vasopressin concentration in the anaesthetized dog before, during and after atrial distension.

Author(s) -

Ledsome J R,

Ngsee J,

Wilson N

Publication year - 1983

Publication title -

the journal of physiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.802

H-Index - 240

eISSN - 1469-7793

pISSN - 0022-3751

DOI - 10.1113/jphysiol.1983.sp014680

Subject(s) - distension , chloralose , vasopressin , medicine , endocrinology , radioimmunoassay , plasma osmolality , plasma concentration , chemistry , anesthesia , blood pressure

Plasma vasopressin (AVP) concentration in dogs anaesthetized with chloralose was measured by radioimmunoassay and was within the range of 2‐5 pg/ml. during control periods. Distension of the left atrium led within 2 min to a fall in plasma AVP concentration which reached a steady lower value within 4 min. After cessation of atrial distension the AVP concentration returned to pre‐distention values within 4 min. Cooling the cervical vagosympathetic nerves to 8‐10 degrees C led to a rise in plasma AVP concentration. Atrial distension during cooling of the vagi resulted in a further increase of plasma AVP concentration.

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