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The reflex respiratory effects on cats of breathing through a tube.
Author(s) -
Marsh J,
Nye P C
Publication year - 1982
Publication title -
the journal of physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.802
H-Index - 240
eISSN - 1469-7793
pISSN - 0022-3751
DOI - 10.1113/jphysiol.1982.sp014154
Subject(s) - chemoreceptor , vagotomy , cats , anesthesia , reflex , ventilation (architecture) , carotid sinus , stimulation , medicine , respiratory system , peripheral chemoreceptors , dead space , breathing , carotid body , anatomy , physics , receptor , thermodynamics
1. In anaesthetized cats, breathing air through an external dead space (a tube, 20‐40 ml.) stimulated ventilation in excess of that expected from the end‐tidal gases. 2. The stimulatory effect remained after bilateral vagotomy. 3. The stimulatory effect was reduced or abolished after bilateral section of the carotid sinus nerves. 4. The stimulatory effect was abolished by bilateral section of both the vagi and the sinus nerves. 5. Recording from chemoreceptor afferents in the sinus nerve showed that, although the tube increased mean discharge frequency, this increase was insufficient to account for the stimulation of ventilation observed. 6. Some feature of chemoreceptor discharge other than its mean level, possibly related to its wave form, may explain the effect.