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Spatial consequences of bleaching adaptation in cat retinal ganglion cells.
Author(s) -
Bonds A B,
EnrothCugell C
Publication year - 1981
Publication title -
the journal of physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.802
H-Index - 240
eISSN - 1469-7793
pISSN - 0022-3751
DOI - 10.1113/jphysiol.1981.sp013868
Subject(s) - bleach , receptive field , adaptation (eye) , retinal , biophysics , stimulation , rhodopsin , concentric , chemistry , peripheral , biology , neuroscience , biochemistry , medicine , mathematics , geometry , organic chemistry
1. Experiments were conducted to study the effects of localized bleaching on the centre responses of rod‐driven cat retinal ganglion cells. 2. Stimulation as far as 2 degrees from the bleaching site yielded responses which were reduced nearly as much as those generated at the bleaching site. Bleaching in the receptive field middle reduced responsiveness at a site 1 degrees peripheral more than bleaching at that peripheral site itself. 3. The effectiveness of a bleach in reducing centre responsiveness is related to the sensitivity of the region in which the bleach is applied. 4. Response reduction after a 0.2 degree bleach followed the same temporal pattern for concentric test spots of from 0.2 to 1.8 degrees in diameter, implying a substantially uniform spread of adaptation within these bounds. 5. A linear trade‐off between fraction of rhodopsin and area bleached over a range of 8:1 yields the same pattern of response reduction, implying that the non‐linear nature of bleaching adaptation is a property of the adaptation pool rather than independent photoreceptors.