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Initiation of the migrating myoelectric complex in dogs.
Author(s) -
Bueno L,
Rayner V,
Ruckebusch Y
Publication year - 1981
Publication title -
the journal of physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.802
H-Index - 240
eISSN - 1469-7793
pISSN - 0022-3751
DOI - 10.1113/jphysiol.1981.sp013789
Subject(s) - duodenum , antrum , jejunum , migrating motor complex , pylorus , anastomosis , stomach , medicine , gastric antrum , small intestine , anatomy , gastroenterology , chemistry , surgery
1. Contractile and spike activity in the conscious dog were recorded from strain gauge force transducers and electrodes chronically implanted on the antrum, duodenum and jejunum. The pattern of activity was related to the time elapsed after feeding a daily meal, both in intact dogs and in dogs with antro‐jejunal or oesophago‐duodenal anastomoses. 2. From 8 to 10 h after feeding, transient reductions of the continuous antral spiking activity were recorded while phases of regular spiking activity (RSA) and contractions developed on the proximal intestine. 3. About 18 h after feeding, the post‐prandial antral activity became intermittent, each period of contractions being accompanied by the duodenal development of a RSA phase. 4. The RSA phases were still initiated on the duodenum after an antro‐jejunal anastomosis and after gastrectomy. 5. It is concluded that phases of RSA of the migrating myoelectric complex are initiated in the proximal part of the small intestine rather than in the stomach. It is suggested that the RSA phase exerts an inhibitory effect on the antrum which may serve to reduce the flow of digesta through the pylorus when the ability of the duodenum to receive chyme is restricted.