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Charge movement and membrane capacity in frog muscle.
Author(s) -
Adrian R H,
Peres A
Publication year - 1979
Publication title -
the journal of physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.802
H-Index - 240
eISSN - 1469-7793
pISSN - 0022-3751
DOI - 10.1113/jphysiol.1979.sp012726
Subject(s) - depolarization , charge (physics) , movement (music) , transient (computer programming) , voltage , membrane potential , chemistry , physics , biophysics , biology , computer science , quantum mechanics , acoustics , biochemistry , operating system
1. The transient current required to impose a step charge of potential has a complex time course especially in the region of internal potential between ‐50 and ‐40 mV. 2. Examination of non‐linear transient current in this voltage range suggests two components of charge movement: (a) an initial more‐or‐less exponential movement, and (b) a slower component with a complex time course. 3. Measurements of membrane capacity support such a division and confirm the steeper voltage dependence of the slower charge movement. 4. Permanent depolarization to 40 mV appears to immobilize the slowly moving charge. Depolarization to ‐20 mV immobilizes both charge movements, and uncovers the presence of a third charge which seems to correspond to Charge 2 (cf. Adrian & Almers, 1976b; Adrian, Chandler & Rakowski, 1976).