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Synaptic potentials recorded from neurones of the submucous plexus of guinea‐pig small intestine.
Author(s) -
Hirst G D,
McKirdy H C
Publication year - 1975
Publication title -
the journal of physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.802
H-Index - 240
eISSN - 1469-7793
pISSN - 0022-3751
DOI - 10.1113/jphysiol.1975.sp011020
Subject(s) - inhibitory postsynaptic potential , excitatory postsynaptic potential , submucous plexus , stimulation , guinea pig , plexus , neuroscience , anatomy , intracellular , electric stimulation , biology , chemistry , myenteric plexus , medicine , endocrinology , microbiology and biotechnology , immunohistochemistry
1. Intracellular recordings have been made from neurones lying in the submucous plexus of guinea‐pig mid small intestine. 2. Most neurones in this plexus receive an extensive excitatory input which could be abolished by tubocurarine. 3. A proportion of neurones also received a single inhibitory input which was activated by transmural stimulation. 4. Some of the characteristics of the inhibitory potentials evoked by transmural stimulation are described. 5. The observations are discussed in relation to the concept of descending excitation (Hirst, Holman & McKirdy, 1975).