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Voltage‐current relationship of a carbachol‐induced potassium‐ion pathway in Aplysia neurones.
Author(s) -
Ginsborg B L,
Kado R T
Publication year - 1975
Publication title -
the journal of physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.802
H-Index - 240
eISSN - 1469-7793
pISSN - 0022-3751
DOI - 10.1113/jphysiol.1975.sp010870
Subject(s) - aplysia , potassium , chemistry , depolarization , carbachol , hyperpolarization (physics) , rectification , biophysics , conductance , voltage , neuroscience , biochemistry , biology , physics , stereochemistry , condensed matter physics , receptor , organic chemistry , quantum mechanics , nuclear magnetic resonance spectroscopy
1. The electrical characteristics of a potassium ion selective pathway produced by the action of carbachol on Aplysia neurones (Kehoe, 1972b) has been studied. 2. The relationship between current and voltage has been found to be non‐linear, the conductance increasing with depolarization and decreasing with hyperpolarization. The degree of rectification was reduced when the external potassium was raised to 50 mM from its normal value of 10 mM. 3. The direction of the rectification and the effect of increased potassium are as predicted by the ‘constant field’ theory, but the degree of rectification is somewhat larger.