Premium
Effect of destruction of the posterior pituitary on the diuresis from left atrial receptors.
Author(s) -
Kappagoda C T,
Linden R J,
Snow H M,
Whitaker E M
Publication year - 1975
Publication title -
the journal of physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.802
H-Index - 240
eISSN - 1469-7793
pISSN - 0022-3751
DOI - 10.1113/jphysiol.1975.sp010824
Subject(s) - diuresis , medicine , stimulation , endocrinology , antidiuretic , receptor , posterior pituitary , kidney , hormone , pituitary gland , chemistry
1. In anaesthetized dogs, stimulation of atrial receptors after destruction of the pituitary gland results in a diuresis. This response was not abolished by the administration of bretylium tosylate and was also observed in a surgically denervated kidney. 2. The diuresis is qualitatively similar to that observed in anaesthetized dogs with intact pituitary glands. 3. It is concluded that the diuresis which results from stimulation of the left atrial receptors is mediated by a blood‐borne agent which is not the antidiuretic hormone.