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A note on the interaction of spontaneous and evoked release at the frog neuromuscular junction
Author(s) -
Barrett Ellen F.,
Barrett J. N.,
Martin A. R.,
Rahamimoff R.
Publication year - 1974
Publication title -
the journal of physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.802
H-Index - 240
eISSN - 1469-7793
pISSN - 0022-3751
DOI - 10.1113/jphysiol.1974.sp010491
Subject(s) - neuromuscular junction , facilitation , anatomy , extracellular , biophysics , neuroscience , chemistry , biology , biochemistry
1. The interaction between spontaneous miniature end‐plate potentials and evoked end‐plate potentials was investigated at the frog neuromuscular junction using focal extracellular recording techniques. 2. End‐plate potentials evoked immediately after a spontaneous miniature potential were facilitated by up to 20%. The percentage facilitation was negatively correlated with the average quantal content of the end‐plate potential.