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Temperature dependence of the ionic current kinetics of Myxicola giant axons
Author(s) -
Schauf C. L.
Publication year - 1973
Publication title -
the journal of physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.802
H-Index - 240
eISSN - 1469-7793
pISSN - 0022-3751
DOI - 10.1113/jphysiol.1973.sp010384
Subject(s) - depolarization , chemistry , sodium , kinetics , potassium , time constant , voltage clamp , analytical chemistry (journal) , membrane potential , biophysics , physics , chromatography , biology , biochemistry , organic chemistry , engineering , quantum mechanics , electrical engineering
1. The temperature dependence of the sodium and potassium conductances of Myxicola giant axons was studied in the range of 1–18° C. 2. Analysis of voltage clamp records for step depolarizations of 20–150 mV yielded Q 10 's for ḡ Na , ḡ K , and g 1 of 1·3–1·5. The steady‐state parameters m ∞ ( v ), n ∞ ( v ) were independent of temperature. The time constants had Q 10 's of: 2·64 ± 0·2 for τ m ; 2·56 ± 0·2 for τ h ; 3·02 ± 0·3 for τ n . 3. τ h determined from the effects of prepulse duration rather than the decline in sodium current during a step depolarization had a Q 10 of 2·47 ± 0·2.