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Effect of lateral cervical cord lesions on the respiratory rhythm of anaesthetized, decerebrate cats after vagotomy
Author(s) -
Remmers John E.,
Tsiaras W. G.
Publication year - 1973
Publication title -
the journal of physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.802
H-Index - 240
eISSN - 1469-7793
pISSN - 0022-3751
DOI - 10.1113/jphysiol.1973.sp010297
Subject(s) - decerebration , medicine , cats , decerebrate state , spinal cord , vagotomy , intercostal nerves , anesthesia , anatomy , respiratory system , reflex , proprioception , cord , stimulation , electric stimulation , surgery , psychiatry , physical therapy
1. The lateral cervical cord of vagotomized, anaesthetized cats was superficially lesioned at the C3 or the C7 level before or after midcollicular decerebration. 2. These cord lesions eliminated the inhibition of diaphragmatic discharge caused by chest compression. Previous work (Remmers, 1973) indicates that this change can be attributed to loss of reflex inhibition of inspiratory activity by intercostal afferents, probably as a result of interruption of tracts ascending in the lateral columns. 3. Decerebrate cats with bilateral cervical cord lesions displayed abnormal respiratory patterns, ranging from apnoea to apneusis. 4. The results are consistent with the hypothesis that the lateral columns carry proprioceptive feed‐back from intercostal mechanoreceptors which promotes rhythmic breathing in the anaesthetized decerebrate cat.