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The effect of splanchnic nerve stimulation on gastric acid secretion and mucosal blood flow in the anaesthetized cat
Author(s) -
Reed J. D.,
Sanders D. J.,
Thorpe Valerie
Publication year - 1971
Publication title -
the journal of physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.802
H-Index - 240
eISSN - 1469-7793
pISSN - 0022-3751
DOI - 10.1113/jphysiol.1971.sp009415
Subject(s) - splanchnic nerves , splanchnic , stimulation , blood flow , gastric acid , stomach , medicine , vagus nerve , endocrinology , chemistry
1. Electrical stimulation of the vagus nerves produced a parallel increase in gastric acid secretion and gastric mucosal blood flow. 2. Gastric acid secretion and mucosal blood flow, stimulated by pentapeptide infusions or by vagal stimulation, were markedly and equally reduced by electrical stimulation of splanchnic nerve fibres. 3. The splanchnic stimulated reduction in acid and mucosal blood flow occurred only when the rise in blood pressure, normally associated with splanchnic stimulation, was prevented by inclusion of a pressure reservoir in the circulation. 4. There was evidence that the effect of the splanchnic nerves was not mediated by release of adrenaline from the adrenal medulla.