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The effect of calcium ions on long chain fatty acid transport by slices of rat jejunum
Author(s) -
Munday K. A.,
Parsons B. J.,
York D. A.
Publication year - 1970
Publication title -
the journal of physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.802
H-Index - 240
eISSN - 1469-7793
pISSN - 0022-3751
DOI - 10.1113/jphysiol.1970.sp009290
Subject(s) - calcium , jejunum , palmitic acid , fatty acid , triglyceride , chemistry , brush border , incubation , biochemistry , biophysics , membrane , biology , cholesterol , vesicle , organic chemistry
1. There is a large increase in palmitic acid uptake by rat jejunum slices when incubated in the presence of calcium. This effect is observed at both 37 and at 0° C. 2. The presence or absence of calcium in the incubation medium does not affect triglyceride synthesis from absorbed fatty acid. 3. The release of synthesized triglyceride from the tissue into the medium is increased by calcium. 4. The probability that calcium transport and long chain fatty acid transport may be interrelated at both the brush border and at the basal and lateral membranes of the intestinal mucosal epithelial cell is discussed.