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The effect of membrane polarization on the time course of the end‐plate current in frog sartorius muscle
Author(s) -
Kordaš M.
Publication year - 1969
Publication title -
the journal of physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.802
H-Index - 240
eISSN - 1469-7793
pISSN - 0022-3751
DOI - 10.1113/jphysiol.1969.sp008926
Subject(s) - sartorius muscle , membrane potential , biophysics , chemistry , membrane , current (fluid) , voltage clamp , intracellular , biology , biochemistry , physics , thermodynamics
1. Intracellular recordings of the end‐plate current at different membrane potentials were made, using a voltage‐clamp technique. 2. When the membrane potential is varied between about +40 and −120 mV, the half‐decline time of the end‐plate current increases from about 0·6 msec to about 1·6 msec. 3. It is suggested that the stability of receptor—mediator complex is affected by the membrane potential.