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Comparison of the effects of water deprivation and sodium chloride imbibition on the hormone content of the neurohypophysis of the rat
Author(s) -
Jones C. W.,
Pickering B. T.
Publication year - 1969
Publication title -
the journal of physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.802
H-Index - 240
eISSN - 1469-7793
pISSN - 0022-3751
DOI - 10.1113/jphysiol.1969.sp008874
Subject(s) - imbibition , sodium , chemistry , hormone , endocrinology , medicine , chloride , biophysics , biochemistry , biology , organic chemistry , botany , germination
1. Vasopressin and oxytocin have been measured in the neurohypophysis of rats which had either been given a 2% (w/v) NaCl solution to drink or been deprived of drinking water for up to 5 days. 2. There was a progressive decrease in the vasopressin content of the glands in both groups; the rates of depletion were not significantly different. 3. Oxytocin also decreased progressively in both groups but the glands from the ‘saline‐treated’ rats contained less hormone than those from the ‘water‐deprived’ animals. 4. The differences in gland content of oxytocin could not be correlated with differences between the plasma osmolalities or sodium concentrations of the two groups.