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Miniature synaptic potentials at frog spinal neurones in the presence of tetrodotoxin
Author(s) -
Colomo F.,
Erulkar S. D.
Publication year - 1968
Publication title -
the journal of physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.802
H-Index - 240
eISSN - 1469-7793
pISSN - 0022-3751
DOI - 10.1113/jphysiol.1968.sp008649
Subject(s) - tetrodotoxin , depolarization , spinal cord , neuroscience , impulse (physics) , subthreshold conduction , biophysics , chemistry , electrophysiology , intracellular , anatomy , biology , physics , voltage , biochemistry , classical mechanics , transistor , quantum mechanics
1. Spontaneous subthreshold potentials have been recorded with an intracellular electrode from neurones of the isolated spinal cord of the frog. 2. Records of both depolarizing and hyperpolarizing potentials were obtained from cells in normal Ringer solution and also when impulse conduction in the cord had been abolished by tetrodotoxin (TTX). 3. Comparisons of results before and after TTX show that the majority of the spontaneous potentials are analogous to miniature end‐plate potentials.