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The effect of haemorrhage on hepatic artery and portal vein flows in the anaesthetized cat
Author(s) -
Greenway C. V.,
Lawson Anne E.,
Stark R. D.
Publication year - 1967
Publication title -
the journal of physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.802
H-Index - 240
eISSN - 1469-7793
pISSN - 0022-3751
DOI - 10.1113/jphysiol.1967.sp008363
Subject(s) - medicine , artery , portal venous pressure , blood flow , vasoconstriction , right gastric vein , vein , portal vein , vasodilation , hepatic portal vein , anesthesia , cardiology , portal hypertension , cirrhosis
1. In cats anaesthetized with pentobarbitone, the hepatic artery and portal vein flows and pressures were recorded simultaneously. 2. Removal of blood from the animal did not cause a decrease in the hepatic artery flow unless the arterial pressure fell below 80 mm Hg. In contrast, the portal vein flow fell markedly. 3. After restoration of the blood, the hepatic artery flow increased to above the pre‐haemorrhage level, while portal vein flow returned only partly towards the control level. 4. It is concluded that haemorrhage causes a vasodilation in the hepatic artery vascular bed and a vasoconstriction in the vascular beds drained by the portal vein. By this means, the oxygen supply to the liver is maintained as far as possible.