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The effect of stress on the concentration of 3β‐hydroxypregn‐5‐en‐20‐one (pregnenolone) and pregn‐4‐ene‐3,20‐dione (progesterone) in the adrenal gland of the rat
Author(s) -
Holzbauer Margarethe,
Newport Helen M.
Publication year - 1967
Publication title -
the journal of physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.802
H-Index - 240
eISSN - 1469-7793
pISSN - 0022-3751
DOI - 10.1113/jphysiol.1967.sp008347
Subject(s) - pregnenolone , corticosterone , endocrinology , medicine , adrenal gland , hormone , chemistry , steroid , biology
1. Pregnenolone and progesterone were estimated in extracts from adrenal glands of rats by gas—liquid chromatography. 2. In unstressed rats their concentrations were found to be smaller than that of corticosterone. 3. Acute stress caused an increase in the concentrations of these steroids which paralleled that of corticosterone.