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Distribution of chylomicrons and albumin in dog kidney
Author(s) -
Pinter G. G.
Publication year - 1967
Publication title -
the journal of physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.802
H-Index - 240
eISSN - 1469-7793
pISSN - 0022-3751
DOI - 10.1113/jphysiol.1967.sp008329
Subject(s) - albumin , chylomicron , kidney , chemistry , distribution (mathematics) , urine , medicine , serum albumin , endocrinology , biochemistry , biology , cholesterol , lipoprotein , mathematical analysis , mathematics , very low density lipoprotein
1. Under specified experimental conditions the distribution space of labelled chylomicrons in the kidney was 13·8 ± 0·9 ml./100 g. tissue. The assumption is supported that this provides a measure for the quantity of intravascular plasma constituents. 2. Values for red blood cells and albumin distribution spaces were 5·2 ± 0·6 and 20·2 ± 1·0 ml./100 g tissue, respectively, in the whole kidney. The ratio of tissue haematocrit over simultaneous arterial haematocrit averaged 0·56. The extravascular albumin fraction amounted to about 31·0% of the total albumin in the whole kidney. 3. A statistically significant correlation was demonstrated between osmotic urine/plasma ( U/P ) ratios (within the approximate limits of 0·6‐1·8) and quantities of extravascular albumin in the medulla.