Premium
The effect of water diuresis on electrolyte excretion in unanaesthetized dogs
Author(s) -
Coxon R. V.,
Ramsay D. J.
Publication year - 1967
Publication title -
the journal of physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.802
H-Index - 240
eISSN - 1469-7793
pISSN - 0022-3751
DOI - 10.1113/jphysiol.1967.sp008240
Subject(s) - excretion , diuresis , electrolyte , potassium , sodium , chemistry , endocrinology , medicine , zoology , natriuresis , chloride , kidney , biology , organic chemistry , electrode
1. The relation between water loading and electrolyte excretion in dogs fed on a meat diet proved impossible to evaluate owing to the large variability in electrolyte excretion rates in control experiments. 2. In animals fed a synthetic diet of constant and known composition the administration of a water load of 2·5% of body weight caused significant increases in the rate of excretion of sodium ( P < 0·01) and potassium ( P < 0·05). The chloride excretion rate also increased in the one animal tested. 3. The significance of these results is discussed.