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The inhibition of induced motor activity in transplanted fundic pouches
Author(s) -
Brown J. C.,
Johnson L. P.,
Magee D. F.
Publication year - 1967
Publication title -
the journal of physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.802
H-Index - 240
eISSN - 1469-7793
pISSN - 0022-3751
DOI - 10.1113/jphysiol.1967.sp008122
Subject(s) - duodenum , chemistry , acetylcholine , motor activity , cholecystokinin , medicine , endocrinology , hydrochloric acid , pharmacology , biochemistry , organic chemistry , receptor
1. An increase in motor activity of transplanted fundic pouches can be produced repeatedly by an alkaline buffer solution in the duodenum. 2. The response can be abolished by small doses of a cholecystokinin‐pancreozymin extract. 3. The secretagogues, olive oil and peptone will inhibit the response when introduced into the duodenum. 4. Acetylcholine in the duodenum will also inhibit the effect. 5. Hydrochloric acid will inhibit the motor activity produced by alkaline buffer in the duodenum and also resting activity of the pouches.