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The effect of amino acids on the intestinal transport of L‐ and D‐xylose in vitro
Author(s) -
Duthie H. L.,
Hindmarsh J. T.
Publication year - 1966
Publication title -
the journal of physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.802
H-Index - 240
eISSN - 1469-7793
pISSN - 0022-3751
DOI - 10.1113/jphysiol.1966.sp008082
Subject(s) - xylose , in vitro , chemistry , amino acid , biochemistry , fermentation
1. The intestinal transport of D ‐xylose by sacs of everted small intestine of the hamster is partially inhibited by L ‐histidine in concentrations of 5, 10 and 20 m M but not of 2 m M . 2. 20 m M concentrations of D ‐histidine and L ‐methionine also produce inhibition. 3. The inhibition is not due to an alteration in water transport or to a change in pH of the incubating medium. 4. The rate of the intestinal transport of L ‐xylose is about ¼ of the rate of D ‐xylose transport and is unaffected by a 20 m M concentration of L ‐histidine.