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The effect of haemorrhage on venous return and regional blood flow in the anaesthetized cat
Author(s) -
Greenway C. V.,
Lawson Anne E.
Publication year - 1966
Publication title -
the journal of physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.802
H-Index - 240
eISSN - 1469-7793
pISSN - 0022-3751
DOI - 10.1113/jphysiol.1966.sp007952
Subject(s) - venous return curve , inferior vena cava , venae cavae , medicine , vasoconstriction , kidney , anesthesia , blood flow , venous blood , anatomy , cardiology , hemodynamics
1. In cats under pentobarbitone anaesthesia, a venous long‐circuit technique was used to measure the blood flows in the superior vena cava and the hepatic, renal and iliac segments of the inferior vena cava. The sum of these flows gave the venous return (minus coronary and bronchial flows). 2. In these preparations, the mean venous return was 130 ml./kg. Of this 28% came from the superior vena cava and 37% from the hepatic, 23% from the renal and 12% from the iliac segments of the inferior vena cava. 3. After haemorrhage, the flows from all the venae cavae segments decreased. The quantitative changes varied with the particular cat, the degree and duration of the haemorrhage and whether the animal had been subjected to a previous haemorrhage. 4. The proportion of the reduced venous return draining from the superior vena cava and the hepatic segment increased, that draining from the renal and iliac segments decreased. Vasoconstriction occurred in all vascular beds, but was greatest in the kidney and hind limbs. Thus the blood flow through the head and liver was partially maintained at the expense of that through the kidneys and hind limbs. 5. Autoregulation of blood flow in the kidneys was usually seen immediately after the first removal of blood but with the onset of renal vasoconstriction it was reduced or abolished for the remainder of the experiment.