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Potentiometric measurement of membrane action potentials in frog muscle fibres
Author(s) -
Frankenhaeuser B.,
Lindley B. D.,
Smith R. S.
Publication year - 1966
Publication title -
the journal of physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.802
H-Index - 240
eISSN - 1469-7793
pISSN - 0022-3751
DOI - 10.1113/jphysiol.1966.sp007857
Subject(s) - potentiometric titration , skeletal muscle fibers , skeletal muscle , membrane , membrane potential , chemistry , biophysics , anatomy , biology , ion , biochemistry , organic chemistry
1. A potentiometric method for recording membrane action potentials from small segments of isolated skeletal muscle fibres has been described. 2. The value of the method in muscle physiology has been appraised by recording from fast and slow skeletal muscle fibres of the frog under a variety of conditions. 3. Artifacts associated with this method have been described and their sources investigated.