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Transfer of propionate by rat small intestine in vitro
Author(s) -
Barry R. J. C.,
Jackson M. J.,
Smyth D. H.
Publication year - 1966
Publication title -
the journal of physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.802
H-Index - 240
eISSN - 1469-7793
pISSN - 0022-3751
DOI - 10.1113/jphysiol.1966.sp007815
Subject(s) - propionate , solvent drag , chemistry , biophysics , electrolyte , permeability (electromagnetism) , biochemistry , membrane , biology , crystallography , microstructure , electrode , grain boundary
1. The transfer of propionate by sacs of rat everted intestine has been investigated in relation to a number of physico‐chemical factors which affect movement of weak electrolytes. 2. Neither the observed movement nor the distribution of propionate can be accounted for by the theory of non‐ionic diffusion or by modifications of it, such as the microclimate hypothesis or partial permeability to ions. 3. It is not possible to account for the observed propionate movement by the electrical potential across the gut or by solvent drag. 4. The most satisfactory explanation for the observations is a transfer process in the gut for volatile fatty acids, and some features of this are discussed.