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Soleus responses to Achilles tendon stimuli are suppressed by heel and enhanced by metatarsal cutaneous stimuli during standing
Author(s) -
Mildren Robyn L.,
Peters Ryan M.,
Carpenter Mark G.,
Blouin JeanSébastien,
Inglis J. Timothy
Publication year - 2021
Publication title -
the journal of physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.802
H-Index - 240
eISSN - 1469-7793
pISSN - 0022-3751
DOI - 10.1113/jp281744
Subject(s) - heel , achilles tendon , soleus muscle , anatomy , foot (prosody) , physical medicine and rehabilitation , medicine , proprioception , electromyography , reflex , tendon , anesthesia , linguistics , philosophy , skeletal muscle
Key points We examined the influence of cutaneous feedback from the heel and metatarsal regions of the foot sole on the soleus stretch reflex pathway during standing. We found that heel electrical stimuli suppressed and metatarsal stimuli enhanced the soleus vibration response. Follow‐up experiments indicated that the interaction between foot sole cutaneous feedback and the soleus vibration response was likely not mediated by presynaptic inhibition and was contingent upon a modulation at the ⍺‐motoneuron pool level. The spatially organized interaction between cutaneous feedback from the foot sole and the soleus vibration response provides information about how somatosensory information is combined to appropriately respond to perturbations during standing.Abstract Cutaneous feedback from the foot sole provides balance‐relevant information and has the potential to interact with spinal reflex pathways. In this study, we examined how cutaneous feedback from the foot sole (heel and metatarsals) influenced the soleus response to proprioceptive stimuli during standing. We delivered noisy vibration (10–115 Hz) to the right Achilles tendon while we intermittently applied electrical pulse trains (five 1‐ms pulses at 200 Hz, every 0.8–1.0 s) to the skin under either the heel or the metatarsals of the ipsilateral foot sole. We analysed time‐dependent (referenced to cutaneous stimuli) coherence and cross‐correlations between the vibration acceleration and rectified soleus EMG. Vibration–EMG coherence was observed across a bandwidth of ∼10–80 Hz, and coherence was suppressed by heel but enhanced by metatarsal cutaneous stimuli. Cross‐correlations showed soleus EMG was correlated with the vibration (∼40 ms lag) and cross‐correlations were also suppressed by heel (from 104–155 ms) but enhanced by metatarsal (from 76–128 ms) stimuli. To examine the neural mechanisms mediating this reflex interaction, we conducted two further experiments to probe potential contributions from (1) presynaptic inhibition, and (2) modulations at the ⍺‐ and γ‐motoneuron pools. Results suggest the cutaneous interactions with the stretch reflex pathway required a modulation at the ⍺‐motoneuron pool and were likely not mediated by presynaptic inhibition. These findings demonstrate that foot sole cutaneous information functionally tunes the stretch reflex pathway during the control of upright posture and balance.