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Silent hypoxaemia in COVID‐19 patients
Author(s) -
Simonson Tatum S.,
Baker Tracy L.,
Banzett Robert B.,
Bishop Tammie,
Dempsey Jerome A.,
Feldman Jack L.,
Guyenet Patrice G.,
Hodson Emma J.,
Mitchell Gordon S.,
Moya Esteban A.,
Nokes Brandon T.,
Orr Jeremy E.,
Owens Robert L.,
Poulin Marc,
Rawling Jean M.,
Schmickl Christopher N.,
Watters Jyoti J.,
Younes Magdy,
Malhotra Atul
Publication year - 2021
Publication title -
the journal of physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.802
H-Index - 240
eISSN - 1469-7793
pISSN - 0022-3751
DOI - 10.1113/jp280769
Subject(s) - covid-19 , presentation (obstetrics) , respiratory distress , hypoxia (environmental) , medicine , respiratory system , distress , intensive care medicine , respiratory failure , case presentation , coronavirus , psychology , anesthesia , virology , surgery , oxygen , clinical psychology , disease , infectious disease (medical specialty) , chemistry , organic chemistry , outbreak
The clinical presentation of COVID‐19 due to infection with SARS‐CoV‐2 is highly variable with the majority of patients having mild symptoms while others develop severe respiratory failure. The reason for this variability is unclear but is in critical need of investigation. Some COVID‐19 patients have been labelled with ‘happy hypoxia’, in which patient complaints of dyspnoea and observable signs of respiratory distress are reported to be absent. Based on ongoing debate, we highlight key respiratory and neurological components that could underlie variation in the presentation of silent hypoxaemia and define priorities for subsequent investigation.