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VGLUT soothes the sour synapse
Author(s) -
Venkatachalam Kartik
Publication year - 2017
Publication title -
the journal of physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.802
H-Index - 240
eISSN - 1469-7793
pISSN - 0022-3751
DOI - 10.1113/jp273469
Subject(s) - exocytosis , neurotransmission , synaptic vesicle , neuromuscular junction , neurotransmitter , microbiology and biotechnology , chemistry , synapse , active zone , biology , neuroscience , biophysics , biochemistry , vesicle , receptor , membrane
When it comes to cations that regulate neurotransmitter release, Ca2+, Na+ and K+ get all the attention. In a sense this is not surprising because the movement of these three cations across presynaptic plasma membranes (PMs) is vital for several aspects of neurotransmission. Whereas flux of Na+ and K+ establishes the resting membrane potential and ensures faithful propagation of action potentials, Ca2+ is arguably most
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