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Are stem cell‐derived neural cells physiologically credible?
Author(s) -
Randall Andrew D.
Publication year - 2016
Publication title -
the journal of physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.802
H-Index - 240
eISSN - 1469-7793
pISSN - 0022-3751
DOI - 10.1113/jp273348
Subject(s) - neuroscience , disease , stem cell , neural stem cell , population , biology , medicine , pathology , genetics , environmental health
This is the author accepted manuscript. The final version is available from Wiley via the DOI in this record.The fast emerging technological advances that are enabling biologists to convert stem cells from various sources into an ever-increasing variety of cell types unquestionably will have far-reaching implications for the future of basic bioscientific research. In time, such technologies will also undoubtedly fundamentally change the nature of clinical intervention in multiple disease areas. Indeed stem cell-related therapies are already a widespread feature of the management of lymphoproliferative disorders and leukaemias and interventions in other diseases are increasingly being investigated both in preclinical studies and in formal clinical trials. [...